According to the authors of a study from Buenos Aires, Argentina, "Impaired left ventricular systolic function (ILVSF) in hypertrophic cardiomyopathy (HC) is a risk factor for sudden death and a determinant of high mortality. We determined its prevalence, clinical parameters, long-term outcome, and pathologic findings of explanted hearts."
"We retrospectively analyzed 382 patients with HC; ILVSF was characterized by LV ejection fraction <50% at rest and was identified in 24 patients (6.3%). Patients with ILVSF were younger than patients with normal SF (43.5 +/- 14.1 vs 55.3 +/- 20.4 years, p = 0.001) and had larger LV end-diastolic cavity diameter (53.2 +/- 12.2 vs 43.8 +/- …
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